Dr. Jithendra Chimakurthy, M. Pharm., Ph. D.
Associate Professor & Head,
Department of Pharmacology
Bapatla College of Pharmacy
Bapatla, Guntur District
Andhra Pradesh – 522101, India
Mobile: +91 98663 94437
Email: jithendrach@gmail.com
Dr Jithendra Chimakurthy has done his bachelor of pharmacy in Vinayaka Mission’s College of Pharmacy, Salem (2002) and Master of Pharmacy in C.L.Baid Metha College of Pharmacy, Chennai (2006), both affiliated to Dr. M.G.R. Medical Univeristy, Chennai. He has obtained his Ph.D from Acharya Nagarjuna University, Guntur (2013). He started his career as a lecturer in Bapatla College of Pharmacy, Bapatla in the year 2006 and has held various positions before taking in charge as the Head of the Department of Pharmacology. His research activities mainly concentrate on CNS disorders and the influence of various bio active molecules on them with emphasis on neurochemical changes in the brain.
Description of research
Dr. Jithendra Ch research was on neuropharmacological effects of curcumin, aethusa cynapium and ginkgo biloba, the effect of these herbal constituents on various CNS disorders were studied during the period of 2007 – 2012 which led to the award of his Ph.D. from Acharya Nagarjuna University, in the year 2013.. The effect of these constituents on various disorders of anxiety such as generalized anxiety disorder, obsessive compulsive disorder and posttraumatic stress disorder were studied. The effect of these constituents on other CNS disorders such as grand mal epilepsy and petit mal epilepsy, catalepsy were studied. The effect of these active constituents on memory and memory disturbances associated with various central nervous system disorders were carried out, a novel animal model for the screening of short term memory was developed. The mechanisms involved in the learning and memory were elucidated and the possible neurotransmitter disturbances that mediate such memory alterations were identified in various research projects conducted in the institution.
- Selected publications
- Jithendra, P.Muralidharan and S.Venkataraman. Anti-hyperglycemic and antioxidant acitivities of the ayurvedic drug premehaoushadhi churnam in alloxan-induced diabetic rats. Int J Green Pharm 2007;1: 26-29.
- Jithendra C, Murthy TEGK, Lokesh U. Protective role of curcumin in maximal electro shock induced seizures, memory impairment and neurotransmitters in rat brain. J Pre-Clin Clin Res 2008;2:35-39.
- Jithendra C, Murthy TEGK, Lokesh U. Effect of curcumin on neuroleptic drug induced catalepsy and memory disturbances. J Pharm Res 2008;1:153-158.
- Jithendra C, Murthy TEGK, Lokesh U. Effect of curcumin on sub-therapeutic doses of AED’s and long term memory in MES induced GTC type of seizures in rats. Res J Pharm Tech 2008;1:401-404.
- Jithendra Ch and P.Muralidharan. Anti-hyperglycemic and antioxidant acitivities of the ayurvedic drug Nisha kathakathadhi churnam in alloxan-induced hyperglycemic rats. Int J Green Pharm2009:3:65-68.
- Jithendra C, Murthy TEGK. Effect of curcumin on quinpirole induced compulsive checking: An approach to determine the predictive and construct validity of the model. North American J Med Sci 2010;2:81-86.
- Jithendra C, Murthy TEGK. Effect of curcumin on pentylenetetrazole-induced anxiety-like behaviors and associated changes in cognition and monoamine levels. Psyc neurosci 2010;3:239-244.
- Jithendra C, Murthy TEGK. Ginkgo biloba extract: Influence on post traumatic stress 2011;1:118-120.
- Jithendra C, Murthy TEGK. Effect of curcumin on statin induced short term memory loss. J Pak Med Students 2012;2:53-57.
- Jithendra C, Murthy TEGK, Lokesh U. Restoration of HPA axis function in rescue of posttraumatic stress disorder in curcumin treated rats. Biomed Int 2011;2:72-80.
- Jithendra C, Hemalatha B, Murthy TEGK Mayuren C. Effect of Costus igneus: The insulin plant, on prediabetes and diabetes in neonatal streptozotocin rats. J Health Sci 2014;4:1-7.
- Jithendra C, Murthy TEGK Effect of aethusa cynapium on quinpirole induced compulsive checking J Chem Pharm Sci 2014;7:95-102.
